|  | 18 Mar | 18:00 EAT | Crystal Palace vs Watford | 1-0 | 1 |
| | 18 Mar | 18:00 EAT | West Ham vs Leicester | 2-3 | X2 |
| | 18 Mar | 18:00 EAT | Sunderland vs Burnley | 0-0 | 1 |
| | 18 Mar | 18:00 EAT | Burton vs Brentford | 3-5 | X |
| | 18 Mar | 18:00 EAT | Wigan vs Aston Villa | 0-2 | 2 |
| | 18 Mar | 19:00 EAT | Nantes vs Nice | 1-1 | X2 |
| | 18 Mar | 20:00 EAT | Torino vs Inter | 2-2 | 2 |
| | 18 Mar | 20:30 EAT | Leeds vs Brighton | 2-0 | 2 |
| | 18 Mar | 20:30 EAT | Bournemouth vs Swansea | 2-0 | 1 |
| | 18 Mar | 20:30 EAT | Alaves vs Real Sociedad | 1-0 | 2 |
| | 18 Mar | 22:00 EAT | Angers vs Guingamp | 3-0 | 1X |
| | 19 Mar | 14:00 EAT | Leganes vs Malaga | 0-0 | 1 |
| | 19 Mar | 17:00 EAT | Bologna vs Chievo | 4-1 | X |
| | 19 Mar | 17:30 EAT | Mainz vs Schalke 04 | 0-1 | 2 |
| | 19 Mar | 19:00 EAT | Dijon vs St Etienne | 0-1 | 1X |
| | 19 Mar | 19:30 EAT | Manchester City vs Liverpool | 1-1 | 1 |
| | 19 Mar | 20:30 EAT | Dep. La Coruna vs Celta Vigo | 0-1 | 1X |
