| C | Time | Home – Away | Score | odds | CS1 | CS2 | |
|---|---|---|---|---|---|---|---|
 | 22:00 UK | Gremio vs Sport Recife | 0-3 | 6.12/8.04 | 2-0 | 2-1 | |
 | 00:30 UK | Santa Fe vs Atl. Nacional | 0-0 | 5.20/6.43 | 1-0 | 2-0 | |
 | 17:30 UK | Iraklis vs Platanias FC | 1-1 | 5.99/5.62 | 0-0 | 1-1 | |
 | 00:00 UK | Santos Laguna vs Chiapas | 2-0 | 7.53/11.33 | 2-0 | 3-1 |